Honors Collegium 70A
Genetic Engineering in Medicine, Law, & Agriculture
Winter 2010


Professor Bob Goldberg

SPONORED BY



Course Documents

 
Course Info:
  Units: 5.0
  Lectures: Tues & Thurs : 3:30 - 6:00 PM
  Discussions: Wed : 12:00 - 2:00 PM TA Daisy Robinton (La Kretz 100)
Wed : 2:00 - 4:00 PM TA Jordan Fischer (La Kretz 100)
Wed : 4:00 - 6:00 PM TA Kristin Gill (La Kretz 100)
  Location: La Kretz 120
 
Class Video
Class Syllabus
 

Class Handouts and Powerpoint Presentation

 

01/06/10 - Lecture-1 Handout(pdf): The Age of DNA: What is Genetic Engineering?

 

01/12/10 - Lecture-2 Handout(pdf) by John Harada: What Are Genes & How Do They Work: Part One

 

01/14/10 - Guest Speaker Handout(pdf) by Robert Wayne: Hunting for Dog Ancestors

 

01/19/10 - Lecture-4 Handout(pdf) by John Harada: What Are Genes & How Do They Work: Part Two

 

01/21/10 - Guest Speaker Handout(pdf) by Richard Hamilton: Engineering Plants For Biofuels

 

01/26/10 - Lecture-5 Handout(pdf) by John Harada: The Age of Genomics: Your Personal Genome

 

01/28/10 - Guest Speaker Handout(pdf) by Alan McHughen: GMOs: What's All The Fuss

 

02/4/09 - Guest Speaker Handout(pdf) by Harry Klann: DNA Forensics and the Law

 

02/9/09 - Lecture-7 Handout(pdf): Identifying Human Origins: Past and Present

 

02/18/10 - Guest Speaker Handout(pdf) by Michele Evans: In Vitro Fertilization and Genetic Testing

 

02/23/10 - Lecture-8 Handout(pdf): Human Genetic Engineering and Gene Therapy

 

03/2/10 - Lecture-9 Handout(pdf)

 

03/4/10 - Guest Speaker Handout(pdf) by John Novembre

 

03/9/10 - Lecture 10 Handout(pdf)

 
Guest Speakers (Click on the name for information about the speaker)
  Dr. Robert Wayne, Ph.D.
UCLA Professor in the Department of Ecology and Evolutionary Biology
Title: Hunting for Dog Ancestors
  Dr. Richard Hamilton, Ph.D.
President and CEO, Ceres, Inc. Thousand Oaks, CA
Title: Engineering Plants For BioFuels
  Dr. Alan McHughen, Ph.D.
CE Plant Biotechnologist, Department of Plant Sciences, UC Riverside
Title: GMOs: What's All The Fuss About?

  Harry Klann
Supervising Criminalist, LAPD
Title: DNA Forensics and the Law
  Dr. Michele Evans, M.D., FACOG
Reproductive Specialist, Huntington Reproductive Center
Title: In Vitro Fertilization (IVF), and Genetic Testing
  Dr. Greg Stock, Ph.D
Bioethicist
Title: Stem Cells: Ethical and Legal Issues
  Dr. John Novembre, Ph.D.
Assistant Professor, Department of Ecology and Evolutionary Biology, UCLA
Title: Tracking Human Ancestry
 
Articles For Discussion
 
Discussion One: The Basics of Genetic Engineering
   

Stanley N. Cohen
The Manipulation of Genes.
Scientific American, July, 1975, 233 (1), 24-33.

   
Clifford Grobstein
The Recombinant DNA Debate.
Scientific American, July, 1977, 237 (1) 22-33.
   
Berg et al.
Potential Biohazards of Recombinant DNA Molecules.
Science, New Series, Vol. 185, No. 4148 (Jul. 26, 1974), 303.
 
Discussion Two: Using Genetic Engineering to Make Drugs in Bacteria
   
Walter Gilbert and Lydia Villa-Komaroff
Useful Proteins From Recombinant Bacteria.
Scientific American, April, 1980, 242 (4), 74-94.
   
William A. Haseltine
Discovering Genes For New Medicine.
Scientific American, March, 1997, 276 (3), 92-97.
 
Discussion Three: Using Genetic Engineering to Make Better Crops.
   
Charles S. Gasser and Robert T. Fraley
Transgenic Crops..
Scientific American, June, 1992, 266 (6), 62-69.
   
Terri Raney and Prabhu Pingali
Sowing a Gene Revolution..
Scientific American, September, 2007, 297 (3), 104-111.
   

Discussion Four: Identifying and Testing for Human Disease Genes
   
Ray White and Jean-Marc Lalouel
Chromosome Mapping with DNA Markers.
Scientific American , February, 1988, 258 (2), 40-48.
   
Mark A. Rothstein
Keeping Your Genes Private.
Scientific American , September, 2008, 299 (3), 64-69.
 
Discussion Five: DNA Testing in the Courtroom
   
Peter J. Neufeld and Neville Colman
When Science Takes the Witness Stand.
Scientific American, May, 1990, 262 (5), 46-53.
   
Jerry Adler and John McCormick
The DNA Detectives.
Newsweek, November 16, 1998, pgs.64-71.
   
 
Discussion Six: Genetic Engineering Farm Animals to Make Drugs
 
William H. Velander, Henryk Lubon, and William N. Drohan
Thansgenic Livestock as Drug Factories.
Scientic American, January, 1997, 276 (1), 70-74.
   
Ian Wilmot
Cloning For Medicine.
Scientific American, December 1998, 279 (6), 58-63.
   
Gary Stix
The Land of Milk & Honey
Scientific American, November 2005, 293 (5), 102-104.
 
Discussion Seven: Embryonic Stem Cell and Cloning for Medicine
   
Clive Cookson et al.,
The Future of Stem Cells..
Scientific American Special Report, July 2005, A6-A21.
   
Jose B. Cibelli, Robert P. Lanza, Michael West, and Carol Ezzell
The First Human Cloned Embryo.
Scientific American, January, 2002, 286 (1), 44-51.
   
Robin Marantz Henig
Pandora's Baby
Scientific American, June, 2003, 266 (6), 63-68. 
 
Discussion Eight: Human Genetic Engineering and Gene Therapy
   
   
Theodore Friedman
Overcoming the Obstacles to Gene Therapy.
Scientific American, June, 1997, 276 (6), 96-101.
   
Steve Mirsky and John Rennie
What Cloning Means for Gene Therapy?
Scientific American, June, 1997, 276 (6), 122-123.
 
Discussion Nine: Science and the Constitution: Regularing Science and GMOs
   
Gary Stix
Traces of a Distant Past.
Scientific American, July, 2008, 298 (6), 56-63.
   
Michael J. Bamshad and Steve E. Olsen
Does Race Exit?
Scientific American, December, 2004, 289 (6), 78-85.
 
Discussion Ten: Science and the Constitution: Who Owns Your Genes?
   
Webster K. Cavenee and Raymond L. White
The Genetic Basis of Cancer..
Scientific American, March 1995, 273 (3), 72-79.
   
Stephen H. Friend and Roland B. Stoughton
The Magic of Microarrays.
Scientific American, February, 2002, 286 (2), 44-53.
   
Francis S. Collins and Anna D. Barker
Mapping the Cancer Genome.
Scientific American, October, 2007, 296 (3), 50-57.