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Course Info: |
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Units: |
5.0 |
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Lectures: |
Tuesday & Thursday : 3:30 - 6:00 PM |
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Location: |
La Kretz 120 |
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Discussions: |
Wednesday: 1-3 PM; 3-5 PM; 5-7 PM (La Kretez 100) |
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Office Hours: |
Friday: 1:30PM - 3:00PM Dr. Bob Goldberg (Terasaki Life Sci 4121) |
Class Syllabus |
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Class Handouts and Powerpoint Presentation
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Week 1
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01/07/20 - Lecture One Handout (pdf): The Age of DNA: What is Genetic Engineering? (Part One)
01/09/20 - Film: Race For the Double Helix
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Week 2
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01/14/20 - Lecture Two Handout (pdf): The Age of DNA: What is Genetic Engineering? (Part Two)
01/16/20 - Films: The Gene Engineers; Designing Life; Genetic Information Age
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Week 3
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01/21/20 - Lecture Three Handout (pdf): What Are Genes & How Do They Work: (Part One)
01/23/20 - Film: Extraordinary Measures
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Week 4
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01/28/20 - Lecture Four Handout (pdf): What Are Genes & How Do They Work: (Part Two)
01/30/20 - Lecture Five Handout (pdf): How Are Genes Cloned & Engineered: The Insulin & Hemophilia Story
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Week 5
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02/04/20 - Lecture Six Handout (pdf): Twenty-First Century Genetic Engineering Applications
02/06/20 - Film: Food Evolution
Guest Speaker: Dr. Channapatna Prakash
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Week 6
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02/11/20 - All-Class Midterm Oral Exam
02/13/20 - Guest Speaker: Harry Klann, Supervising Criminologist, DNA Unit, LAPD, Retired
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Week 7
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02/18/20 - Lecture Seven Handout (pdf): Age of Genomics: Three Parent Babies, Human Origins, and Race
02/20/20 - Guest Speaker: Stem Cell Biology and Ethics by Dr. Pei Yun Lee
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Week 8
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02/25/20 - Lecture Eight Handout (pdf): Human Genetic Engineering & Gene Therapy
02/27/20 - Guest Speaker: In Vitro Fertilization and Genetic Testing by Dr. Michele Evans
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Week 9
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03/03/20 - Lecture Nine Handout (pdf): Science & the Constitution: Regulating Science & GMO
03/05/20 - Guest Speaker: The Future of Genetic Engineering & Health by Dr. Daisy Robinton
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Week 10
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03/10/20 - Lecture Ten Handout (pdf): Science & the Constitution: Who Owns Your Genes
03/12/20 - All-Class Final Oral Exam
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Articles For Discussion |
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Discussion One: What Do You Think About Genetic Engineering and GMOs?
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Discussion Two: Origins of Genetic Engineering - Hybrid DNA Molecules and Controversy
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1. Stanley N. Cohen, The Manipulation of Genes, Scientific American, June, 1992, 233(1), 24-33.
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2. Clifford Grobstein, The Recombinant DNA Debate, Scientific American, July, 1977, 237(1), 22-33.
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Discussion Three: Origins of Biotechnology - From Genes to Drugs
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1. Walter Gilbert and Lydia Villa-Komaroff, Useful Proteins From Recombinant Bacteria, Scientific American, April, 1980, 242(4), 74-94.
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Discussion Four: Origins of Biotechnology - From Genes to Drugs
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1. Richard M. Lawn, & Gordon A. Vehar, The Molecular Genentics of Hemophilia, Scientific American, March, 1986, 254(3), 48-54.
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Discussion Five: Genetic Engineering Crops & Farm Animals
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1. David H. Freedman, Are Geneticcally Engineered Foods Evil?, Scientific American, September, 2013, 80-85.
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2. William H. Velander, Henryk Lubon, & William N. Drohan, Transgenic Livestock as Drug Factories, Scientific American, January 1997, 276(1), 70-74.
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3. Carolyn Y. Johnson, Gene Edited Farm Animals Are Coming, The Washington Post, December 17 2018.
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4. Emily Waltz, GM Salmon Declared Fit For Dinner Plates, Nature Biotechnology, January 2016, 7-9.
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Discussion Six: DNA and the Law
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1. Peter J. Neufeld & Neville Coleman, When Science Takes the Witness Stand, Scientific American, May, 1990, 262(5), 46-53.
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2. Heather Murphy, Cousin's DNA and Family Trees to Crack Cold Cases, The New York Times, June 27, 2018.
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3. Jamie Ducharme, Gentic Databases Could Identify Millions of Americans, Time Magazine, October 12, 2018.
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Discussion Seven: How to Mark Your Genes
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1. Ray White & Jean-Marc Lalouel, Chromosome Mapping with DNA Markers, Scientific American, February 1988, 258(2), 40-48.
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2. Kevin A. Strauss, Genomics for the People, Scientific American, December 2015, 313(6), 66-73.
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3. Bonnie Rochman, Should Babies Be Sequenced? Scientific American, March 2017, 316: 72-75.
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Discussion Eight: Human Gene Therapy - The Beginning
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1. Inder M. Verma, Gene Therapy. Scientific American, November, 1990, 263(5), 68-84.
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2. Rick Lewis, Gene Therapy's Second Act, Scientific American, March 1, 2014, 310(3).
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Discussion Nine: Human Gene Therapy - Twenty-First Century Applications
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1. Leonard Petrucelli & Aaron D. Gitler, Unlocking The Mystery of ALS, Scientific American, June, 2017.
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2. Lydia Denworth, Finally Making Sense, Scientific American, March, 2020.
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3. Carrie Arnold, Treatment for ALS Poised to Move Ahead, Nature, February 26, 2020.
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Discussion Ten: The CRISPR Revolution
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1. Michael Specter, DNA Revolution, National Geographic Magzine, August 2016, 31-55.
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2. Carolyn Y. Johnson, Chinese Scientist's Claim of Gene-edited Babies Creates Uproar, The Washington Post, November 26, 2018.
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3. Ariana E. Cha This Fertility Doctor is Pushing the Boundaries of Human Reproduction with Little Regulation, The Washington Post, May 14, 2018.
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