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Goldberg Lab News

Lab Reopens After COVID-19 Shutdown

After suspending benchwork in mid-March due to the Covid-19 pandemic, our lab has been approved to ramp up our lab-based research in the near future. Both the University of California, Los Angeles and the College of Life Sciences have provided extensive guidance on necessary safety measures and we are confident we can resume research activities using these precautions.

Lab Administrator Lauren Bowman Receives Doctorate

Lauren defended her dissertation in the fall of 2017, and was hooded at the University of Illinois at Chicago on May 14th. She has been part of Goldberg Lab since January of 2014.

Dr. Goldberg Moderates GMO Documentary Panel

On November 21st, Dr. Goldberg acted as moderator for a panel discussion following a screening of the documentary 'Food Evolution' at the Hammer Museum in Westwood. The panel, which included Dr. Neil DeGrasse Tyson, director Scott Kennedy, and Bill Nye the Science Guy, had a lively and informative discussion, taking questions from the audience about both the social and scientific implications of GMOs.

Click here to watch the post-movie panel.

Remembering Dr. Goldberg's Mentor, Professor Norm Cohn

At a research symposium on September 9th, former students and colleagues gathered in Athens, Ohio to pay tribute to Ohio University Distinguished Professor Emeritus Dr. Norman S. Cohn. Dr. Cohn was instrumental in shepherding many Ohio University students into science careers, including Dr. Bob Goldberg. Alongside Dr. Ralph Quatrano and Dr. Dean Dellapena, Dr. Goldberg formally presented the Norman S. Cohn Research Fellowship in Plant Cell and Molecular Biology to Stacy Welker, the first undergraduate to receive the fellowship that these three former students endowed.

Click here to read an article about the symposium.

Symposium to Celebrate Dr. Bob Fischer's Career

Science and celebration were the focus of a symposium the weekend of April 22-23rd at the UCLA Luskin Conference Center. Former undergraduate, graduate, and postdoctoral students gathered to honor Dr. Fischer's career and share their research, illustrating Dr. Fischer's scientific legacy in action.

Dr. Goldberg Takes Part in Zocalo Panel on GMOs

Dr. Bob Goldberg was part of a Zocalo panel regarding the safety and public perception of GMOs on Wednesday, December 14th. The lively discussion highlighted the disconnect between the public's fear of GMOs and the considerable scientific data supporting their safety.

Click here to read the full article.

New Video About Bob Goldberg's Classes

Take a moment to check out this fun new video about Dr. Goldberg's HC70A and HC70AL courses at UCLA!

Click here to view the video.

Bob Goldberg Gives the Hales Award Lecture on Seeds of Hope: Back to the Future at the ASPB Annual Meeting in Austin Texas on July 9, 2016

Dr. Bob Goldberg gave the Stephen Hales Award Lecture on the opening day of the ASPB conference, delivering a talk that encompassed discussion of GMO's, the growing food needs of the world, and his lab's current research.

Click here to view photos of the talk.

Dr. Goldberg Featured on Honors Programs Home Page

An image of Dr. Goldberg in the midst of teaching is featured on the home page of UCLA Honors Programs. Dr. Goldberg has had the privilege of teaching in the Honors Collegium for 13 years.

Click here to view the home page.

Dr. Goldberg Quoted in article about GMOs

Following a talk at Founders Hall in Calabasas titled 'Seeds of Hope: Genetics and the Future of Agriculture', Dr. Goldberg is quoted in a story in The Acorn regarding public understanding of GMOs.

Click here to read the full article.

Discovery Science Center

Dr. Goldberg spoke at the Thousand Oaks High School Performing Arts Center on October 8th, educating students and community members about genetically modified organisms and their role in feeding an increasingly hungry world.

Click here for a flyer outlining The Discovery Center's Science Speaker Series.

2015 Stephen Hales Prize awarded to Bob Goldberg

Bob Goldberg has been selected as the recipient of the 2015 American Society of Plant Biologists Stephen Hales Prize, which is "a monetary award established in 1927 for a scientist, whether or not a member of the Society, who has served the science of plant biology in some noteworthy manner."

Click here for ASPB's announcement regarding the award.

Bob Goldberg gives an invited lecture at the Center for Inquiry-Los Angeles on the topic of GMOs

"In a 'Feed Your Brain' Lecture at CFI-Los Angeles, UCLA Prof. Bob Goldberg told a full house about the validity of the science of genetically modified organisms (GMOs), and the mythologies being spread about their alleged dangers."

Click here for a brief overview of his lecture.

Bob Goldberg quoted in LA Times article covering the LA City Council's decision to ban growing GMOs in the city

"In an interview, Bob Goldberg, a UCLA plant molecular biologist and a member of the National Academy of Sciences, said that genetically modified crops are no different from those that farmers have been selectively breeding for centuries, and they pose no added health risk. 'There's not been one documented case of a sneeze from anyone eating a genetically modified papaya,' he said."

Click here for full article.

Plant Developmental Biology Symposium at UCLA held in honor of Bob Goldberg's 40 year career in plant molecular biology

On April 11, 2014, over 150 students and scientists from all over the world gathered at UCLA to participate in a one day symposium on plant developmental biology, focusing specifically on the seed. Two prominent figures in the field, Dr. Marc Van Montagu and Dr. Eric Davidson, provided keynote talks, while various former Goldberg lab members and colleagues presented research.

Click here for more info or to watch video of the symposium presentations.


Using 454 Sequencing to Survey The Transcriptome of Soybean Seeds
Containing Globular-Stage Embryos

We carried out a pilot study using the high-throughput 454 sequencing (454 Life Sciences) to survey the transcriptome of a globular-stage soybean seed. ~900,000 reads were generated with the average length of 200 bases in one run representing a deep sampling of the globular-stage seed transcriptome. Raw unprocessed EST sequences generated from this study have been submitted to Genbank Short Read Archive (SRA) division under accession number SRA001022. The processed EST sequences also have been submitted to Genbank dbEST division under accession numbers FK265369 to FK668879 and GD660863 to GE139779.

Click here to learn more about this study and download 454 EST sequences

Updated Soybean GeneChip Array Annotation

We annotated the Affymetrix Soybean Genome GeneChip Array using information from TAIR, TIGR, and Peking Transcription Factor databases. The current version of annotation was updated as of October 2007. Please check the link below to access the annotation and detailed description.

Click here to download our new annotation file and detailed description.

NSF Single Cell Genome Profiling Project in Soybean

We used laser capture microdissection to isolate specific compartments, tissues, and cell types from soybean seeds at different stages of development – including the seed coat, endosperm, and embryo regions and organ systems. Microarray, EST sequencing, and qRT-PCR experiments are carried out in order to determine (1) the spectrum of genes and processes that are active in different parts of the seed and (2) how transcription factors are partitioned within a seed. Functional studies are also carried out in order to determine what role compartment and tissue-specific transcription factors play in soybean seed development. Data generated from this NSF-sponsored project are continuously updated in our interactive relational seed database - Gene Networks in Seed Development. Please check out this web site for up-to-date information about this project.

Click here to browse our database - Gene Networks in Seed Development.

Genomic Profiling of Arabidopsis Plant Life Cycle Using Affymetrix GeneChips

Utilizing a genomics approach, we profiled mRNAs active during Arabidopsis seed development using whole-genome Affymetrix GeneChips ATH1-121501. Specifically, we profiled mRNAs active during seed development at 24 hour post-fertilization, 7-8 days after pollination (DAP), 13-14 DAP, and 18-19 DAP. These gene sets were compared with those active in pre-fertilization ovules, seedlings 3 days after imbibition, leaves, roots, stems, and floral buds of the mature plant. Collectively, we have carried out whole-genome analysis of genes active during the entire Arabidopsis life cycle.

Click here to browse our Arabidopsis GeneChip Database

Scarlet Runner Bean Embryo EST Project

We have identified ~390,000 ESTs representing messages active 6-7 days after fertilization in different regions of early embryos. See a catalog of embryo-proper and suspensor ESTs found to date.

Click Here to Visit Scarlet Runner Bean Embryo EST Project Website.

We've also created a database where you can query your sequences against our Scarlet Runner Bean ESTs using local BLAST tools.

Click Here to BLAST Your Sequences Against our Scarlet Runner Bean EST Sequences.

All of our EST sequences have been submitted to GenBank. Their accession numbers are: CA896559 to CA916678 and GD289845 to GD660862. You can access all of these sequences at NCBI.

Click Here for Access to Scarlet Runner Bean ESTs in the GenBank.


PhD Student Kelli Henry Successfully Defends Thesis

Kelli Henry successfully defended her thesis, entitled "Identifying cis-Regulatory Elements and trans-Acting Factors that Activate Transcription in the Suspensor of Plant Embryos" on May 30th in front of a four person committee at UCLA, including Chair Dr. Bob Goldberg. Dr. Henry's work on scarlet runner beans contributes new knowledge to the field of plant genetics concerning the gene regulatory networks governing seed development. She plans to continue this focus on understanding seed development in her future research.

New Plant Knockout and Genomics Lab Manual For Undergraduates Avaliable

HC70AL, Gene Discovery Laboratory, is a novel laboratory taught by Professor Bob Goldberg that is designed to teach entering life sciences students and non-science majors at all levels the excitement of discovery. In this laboratory, each student identifies an Arabidopsis transcription factor gene active in specific seed compartments, and uses a variety technologies to determine what effect, if any, knocking out these genes has on seed development. An HC70AL, Gene Discovery Laboratory Manual is organized into a 10-week series of gene discovery experiments designed for students with no previous laboratory experience. A pdf file containing the entire Spring 2011 HC70AL laboratory manual can be downloaded by clicking on the link below. If you use this laboratory manual, we would appreciate that you cite Professor Bob Goldberg, Dr. Kelli Henry, Dr. Anhthu Bui, Dr. Brandon Le, and other members of our laboratory who contributed to putting the laboratory manual together. In addition, we would appreciate it if you would send an email to Professor Bob Goldberg (bobg@ucla.edu) and outline for what course the manual is being used.

Click here to view the Plant Knockout and Genomics Lab Manual for Undergraduates.

The World's A Classroom? Thanks to Technology, It Can Be

March 19, 2009 - Professor Robert B. Goldberg told UCLA Newsroom reporter, "There is the potential to bring people from different parts of the globe together in a global village of education. What an amazing experience for the students! Imagine the cultural differences. We can give students experiences that they would never have." His class, HC70A (Genetic Engineering in Medicine, Agriculture, and Law), is a really good model for interactive higher education teaching. Read more.

Also you can read the story on National Science Foundation (NSF) website. Click the image below to read more.

BOB GOLDBERG'S HC70A:Genetic Engineering in Medicine, Agriculture, and Law

Since 2009, HC70A has been taught simultaneously to students at both UCLA and UC Davis by using videoconferencing software to link campuses together over the internet. In 2011, students at Tuskegee University began participating in HC70A lectures and discussions carried out in real time via the software that allows simultaneous video and audio interactions among Bob Goldberg and his students on all three campuses. UCLA, UC Davis, and Tuskegee students interact with one another during the lectures. In addition, UC Davis students and Tuskegee students visited UCLA for two days and participated the lecture and discussion session during the quarter.

Click here to view Bob Goldberg's HC70A UCLA - UC Davis long distance learning class syllabus.

Click here to read the article about Bob Goldberg's HC70A in UCLA Newsroom.

Click here to view the posted lectures on YouTube.

Funded by National Science Foundation

This program contains two courses: HC70A and HC70AL, which specifically targets non-science majors and teaches them about science.

HC70A: Genetic Engineering in Medicine, Agriculture, and Law

HC70A course introduces scientific concepts in a classroom setting, through lectures, articles and in class demonstrations. Students learn the foundations of molecular biology, and discuss the ethical, legal, and social implications that result from emerging genomic technologies.

Click here to browse HC70A website of Winter 2020

HC70AL: Gene Discovery Laboratory

HC70AL course invites students from the HC70A course to apply the state-of-the-art genomics techniques learned in the class to a real life experience. The Gene Discovery Laboratory teaches students who have never worked in a laboratory how to carry out an original research project, analyze data critically, and communicate results to their peers.

Click here to browse HC70AL website of Summer 2014

Planting the Seeds of Discovery

As an HHMI Professor, he plans to design and teach a course that will show students who are not science majors the numerous ways science has an impact on society, for example, the social, legal and ethical issues that arise from emerging new genetic technologies.

Howard Hughes Medical Institute's Million-Dollar Professors

What would you do with a million dollars? Twenty scientists at research universities across the nation have 20 different answers. They all share a goal, however: to make science more engaging for undergraduates. Read more


The Hungry Earth

Robert Goldberg discusses plant development in The Hungry Earth article for UCLA Magainze.

UCLA Office of Intellectual Property

Robert Goldberg is interviewed for an article about genomics for the UCLA Office of Intellectual Property magainze.

UCLA Newsroom
The World's A Classroom? Thanks to Technology, It Can Be

March 19, 2009 -- Professor Robert B. Goldberg told UCLA Newsroom reporter, "There is the potential to bring people from different parts of the globe together in a global village of education. What an amazing experience for the students! Imagine the cultural differences. We can give students experiences that they would never have." His class, HC70A (Genetic Engineering in Medicine, Agriculture, and Law), is a really good model for interactive higher education teaching. Read more.

Los Angeles Times Daily News

December 5, 2004 -- During the next 50 years, we will need to produce more food than in the entire history of mankind. And we will need to do this on a rapidly shrinking amount of land that is suitable for agriculture...Read more

Bob Goldberg Elected into the National Academy of Science

UCLA plant biologist Robert B. Goldberg was elected today to the prestigious National Academy of Sciences "in recognition of his distinguished and continuing achievements in original research," the academy announced Tuesday...Read more

Los Angeles Times Interview by Greg Goldin
Robert Goldberg: Seeds of Contention

Sunday, September 2, 2001. UCLA molecular biologist Robert B. Goldberg wants to understand in plants what stem-cell researchers want to understand in humans: How the undifferentiated molecules of a seed develop from nearly identical dabs into highly specialized plant parts...Read more


UCLA Public Policy Guest Lecture
Presentation by Dr. Bob Goldberg

GMOs have been a public policy issue since the discovery of genetic engineering. In a lecture for a UCLA public policy course, Dr. Goldberg explores the intersection of GMOs, government and society. >

Biotechnology Cluster Guest Lecture
Presentation by Dr. Bob Goldberg

What do GMOs mean for the world today, tomorrow, and in the future? Dr. Goldberg's guest lecture for Dr. Rensel's Biotechnology Cluster course examines this topic.

UCLA Parent's Weekend 2013
Presentation by Dr. Bob Goldberg

Gain a better understanding of how genetically engineered crops can positively impact world hunger and the future of our society by viewing Dr. Goldberg's UCLA Parent's Weekend 2013 presentation on genetic engineering in plants.

Seed Development Movie
Created by Brandon Le and Dr. Goldberg

Explore the Life Cycle of a Plant. Click the picture to view the movie. This Movie is best viewed in Quicktime.

History's Harvest: Where Food Came From

Explore the History of Agriculture and the Evolution of the Foods We Eat Today. Click here to check out clips from the movie.

UCLA Science Faculty Research Colloquium

The UCLA Science Faculty Reserach Colloquium Series is designed to promote interdiscriplinary collaborative research, highlight the research of exceptionally distinguished faculty, and enhance education about significant new research in the sciences. The Series is sponsored by the Divisions of Life and Physical Sciences, UCLA College.

What Are the Genes Required to Make a Seed?
Wednesday, May 21, 2008
4:00 PM PST

Click the following links to watch the talk on YouTube: Part One and Part Two

Keck Genomics Symposium

Foods for the Future: Genomics of Bioengineered Foods

Sponsored by the W. M. Keck Foundation. Offered in cooperation with the Office of Continuing Medical Education David Geffen School of Medicine at UCLA and UCLA Extension.

87th Faculty Research Lecture

The annual Faculty Research Lectures of the Univeristy of California, Los Angeles present to the public our most distinguished scholars. It is our purpose to accord them the high recognition that is their due, and further to give our faculty, students and the citizens of this community an opportunity to understand the scholarly achievements and points of view of those whom we honor.

Genetic Engineering in Agriculture: Super Plants for the 21st Century

Robert B. Goldberg
Professor of Molecular, Cell and Developmental Biology
Thursday, December 2, 1999
3:00 - 4:30 PM PST
(Live Webcast)