Publications
Publications
Cardiac Patterning Related Publications from the Chen Lab
Langenbacher A Nguyen CT, Cavanaugh A, Huang J, Lu F and Chen JN (2011) The PAF1 complex differentially regulates cardiomyocyte specification. Developmental Biology, 353: 19-28.
Nguyen C*, Langenbacher A*, Hsieh M and Chen JN (2010) The PAF1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish. Developmental Biology, 341: 167-175.
* equal contribution.
Shu X*, Huang J*, Dong Y*, Choi J, Langenbacher A and Chen JN (2007) Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning. Development, 134: 1921-1930. * equal contribution.
Cibrian-Uhalte E, Shu X, Langenbacher A, Chen JN and Abdeliah-Seyfried S (2007) Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance. Journal of Cell Biology, 176: 223-230.
Mably JD, Chuang, LP, Serluca, FC, Mohideen MAPK, Chen JN and Fishman, MC (2006) santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish. Development 133: 3139-3146.
Beis D, Bartman T, Jin SW, Scott IC, D’Amico LA, Ober EA, Verkade H, Frantsve J, Field HA, Wehman A, Baier H, Tallafuss A, Bally-Cuif L, Chen JN, Stainier DYR and Jungblut B. (2005) Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development 132, 4193-4204.
Chen JN, Crowan DB and Mably J (2005) Cardiogenesis and the regulation of cardiac-specific gene expression. Heart Failure Clin.; 1, 157-170.
Huang H, Zhang B, Hartenstein PA, Chen JN and Lin S (2005) NXT2 is required for embryonic heart development in zebrafish. BMC Developmental Biology, 5: 7.
Mably J, Chen JN, Mohideen MA and Fishman MC (2003) heart of glass regulates the concentric growth of the heart in zebrafish. Current Biology, 13: 2138-2147.
Shu X, Cheng K, Patel N, Chen F, Tsai HJ and Chen JN (2003) Na,K-ATPase is essential for embryonic heart development in the zebrafish. Development, 130: 6165-6173.
Peterson RT, Mably JD, Chen J-N and Fishman MC (2001) Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Current Biology 11, 1481-1491.
Chen J-N, van Bebber F, Goldstein AM, Serluca FC, Jackson D, Childs S, Serbedzija G, Warren KS, Mably JD, Lindahl P, Mayer A, Haffter P and Fishman MC. (2001) Genetic steps to organ laterality in zebrafish. Comparative and Functional Genomics: 2: 60-68.
Chen J-N and Fishman MC (2000) Genetics of heart development. Trends in Genetics 16: 383-388.
Chen J-N and Fishman MC (2000) Genetic dissection of heart development. In Fish, Fly, Worm and man. Ernst Schering Research Foundation, 107-122.
Park M, Lewis C, Turbay D, Chung A, Chen J-N, Evans S, Breitbart RE, Fishman MC, Izumo S and Bodmer R. (1998) Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes. Proc. Natl. Acad. Sci. USA 95: 9366-9371.
Serbedzija GN, Chen J-N, Fishman MC. (1998) Regulation in the heart field of zebrafish. Development 125:1095-1101.
Chen J-N, Fishman MC. (1997) Genetic dissection of heart development. In: Burggren W, Keller B, eds. Development of Cardiovascular System: Molecules to Organisms. Cambridge Press, 7-17.
Chen J-N, van Eeden FJM, Warren KS, Chin AJ, Nüsslein-Volhard C, Haffter P and Fishman MC. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373 - 4382.
Chin AJ, Chen J-N and Weinberg ES. (1997) Bone morphogenetic protein-4 expression characterizes inductive boundaries in organs of developing zebrafish. Devel. Genes and Evolu. 207: 107-114.
Stainier DYR, Fouquet B, Chen J-N, Warren K S, Weinstein B M, Meiler S, Mohideen MAPK, Neuhauss SCF, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W and Fishman MC. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development 123: 285-292.
Chen J-N, Haffter P, Odenthal J, Vogelsang E, Brand M, van Eeden FJM, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Kelsh RN, Mullins MC and Nusslein-Volhard C. (1996) Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123: 293-302.
Chen J-N and Fishman MC. (1996) Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122: 3809-3816.