Publications

 

Cardiac Rhythmicity Related Publications from the Chen Lab

Sun H, Lu G, Ren V, Chen JN and Wang Y (2011) Catabolism of branched-chain amino acids in heart failure: insights from genetic models. Journal of Pediatric Cardiology 32:305-310.


Yu F, Huang J, Adlerz K, Jadvar H, Hamdan M, Chen JN and Hsiai T (2010) Evolving cardiac conduction phenotypes in developing zebrafish larvae: implications to drug sensitivity.  Zebrafish, 7: 325-331.


Nguyen CT, Lu Qing, Wang Y and Chen JN (2009) Zebrafish as a model for cardiovascular development and disease. Drug Discovery Today: Disease Models, 5: 135-140.


Xie Y, Ottolia M, John S, Chen JN and Philipson KD (2008) Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. Am J Physiol Cell Physiol. 295: C388-393.

Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y (2007) A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes and Development, 21: 784-796.

Langenbacher AD, Dong Y, Shu X, Choi J, Nicoll DA, Goldhaber JI, Philipson KD and Chen JN (2005) Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. PNAS, 102: 17699 - 17704.

Chen JN, Crowan DB and Mably J (2005) Cardiogenesis and the regulation of cardiac-specific gene expression. Heart Failure Clin.; 1, 157-170.

Huang H, Zhang B, Hartenstein PA, Chen JN and Lin S (2005) NXT2 is required for embryonic heart development in zebrafish. BMC Developmental Biology, 5: 7.

Mably J, Chen JN, Mohideen MA and Fishman MC (2003) heart of glass regulates the concentric growth of the heart in zebrafish. Current Biology, 13: 2138-2147.

Shu X, Cheng K, Patel N, Chen F, Tsai HJ and Chen JN (2003) Na,K-ATPase is essential for embryonic heart development in the zebrafish. Development, 130: 6165-6173.

Chen J-N and Fishman MC (2000) Genetics of heart development. Trends in Genetics 16: 383-388.

Chen J-N and Fishman MC (2000) Genetic dissection of heart development. In Fish, Fly, Worm and man. Ernst Schering Research Foundation, 107-122.

Chen J-N, Fishman MC. (1997) Genetic dissection of heart development.  In: Burggren W, Keller B, eds. Development of Cardiovascular System: Molecules to Organisms.  Cambridge Press, 7-17.

Stainier DYR, Fouquet B, Chen J-N, Warren K S, Weinstein B M, Meiler S, Mohideen MAPK, Neuhauss SCF, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W and Fishman MC. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development 123: 285-292.

Chen J-N, Haffter P, Odenthal J, Vogelsang E, Brand M, van Eeden FJM, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Kelsh RN, Mullins MC and Nusslein-Volhard C. (1996) Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123: 293-302.

Chen J-N and Fishman MC. (1996) Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122: 3809-3816.