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Course Info: |
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Units: |
5.0 |
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Lectures: |
Tuesday & Thursday : 3:30 - 6:00 PM |
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Location: |
La Kretz 120 |
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Discussions: |
Wednesday: 1:00 - 2:50 PM (La Kretz 100)
Wednesday: 3:00 - 4:50 PM (La Kretz 100)
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Office Hours: |
Friday: 1:00PM - 2:30PM Dr. Bob Goldberg (Terasaki Life Sci 4121)
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Class Handouts and Powerpoint Presentation
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Week 1
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01/09/18 - Lecture One Handout (pdf): The Age of DNA: What is Genetic Engineering? (Part One)
01/11/18 - Film: Race For the Double Helix
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Week 2
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01/16/18 - Lecture Two Handout (pdf): The Age of DNA: What is Genetic Engineering? (Part Two)
01/18/18 - Film: Extraordinary Measures
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Week 3
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01/23/18 - Lecture Three Handout (pdf): What Are Genes & How Do They Work: (Part One)
01/25/18 - Guest Speaker: Dr. Richard Hamilton
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Week 4
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01/30/18 - Lecture Four Handout (pdf): What Are Genes & How Do They Work: (Part Two)
02/01/18 - Film: Food Evolution
Guest Speaker: Scott Hamilton Kennedy, Drictor "Food Evolution"
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Week 5
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02/06/18 - Lecture Five Handout (pdf): How Are Genes Cloned & Engineered: The Hemophilia Story
02/08/18 - Guest Speaker: Harry Klann, Supervising Criminologist, LAPD DNA Unit
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Week 6
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02/13/18 - All-Class Midterm Oral Exam
02/15/18 - Film: Knowledge or Certainty
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Week 7
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02/20/18 - Lecture Six Handout (pdf): Twenty-First Century Genetic Engineering Applications
02/22/18 - Lecture Seven Handout (pdf): Age of Genomics: Three Parent Babies, Human Origins, and Race
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Week 8
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02/27/18 - Lecture Eight Handout (pdf) by Dr. John Harada: Human Genetic Engineering & Gene Therapy
03/01/18 - Guest Speaker: Stem Cell Biology and Ethics by Dr. Pei Yun Lee
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Week 9
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03/06/18 - Lecture Nine Handout (pdf): Science & the Constitution: Regulating Science & GMO
03/08/18 - Guest Speaker: The Future of Genetic Engineering & Health by Dr. Daisy Robinton
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Week 10
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03/13/18 - Lecture Ten Handout (pdf): Science & the Constitution: Who Owns Your Genes
03/15/18 - All-Class Final Oral Exam
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Articles For Discussion |
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Discussion One: What Do You Think About Genetic Engineering and GMOs?
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Discussion Two: Origins of Genetic Engineering - 1
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1. Stanley N. Cohen, The Manipulation of Genes, Scientific American, June, 1992, 233(1), 24-33.
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2. Clifford Grobstein, The Recombinant DNA Debate, Scientific American, July, 1977, 237(1), 22-33.
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Discussion Three: Origins of Genetic Engineering - 2
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1. Walter Gilbert and Lydia Villa-Komaroff, Useful Proteins From Recombinant Bacteria, Scientific American, April, 1980, 242(4), 74-94.
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Discussion Four: Genetic Engineering Crops & Farm Animals
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1. David H. Freedman, Are Geneticcally Engineered Foods Evil?, Scientific American, September, 2013, 80-85.
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2. William H. Velander, Henryk Lubon, & William N. Drohan, Transgenic Livestock as Drug Factories, Scientific American, January 1997, 276(1), 70-74.
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3. Emily Waltz, GM Salmon Declared Fit For Dinner Plates, Nature Biotechnology, January 2016, 7-9.
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Discussion Five: DNA and the Law
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1. Peter J. Neufeld & Neville Coleman, When Science Takes the Witness Stand, Scientific American, May, 1990, 262(5), 46-53.
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2. Caitlin Smith, Stephen Strauss, & Laura DeFrancesco, DNA Goes to Court, Nature Biotechnology, November, 2012, 30(11), 1047-1052.
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3. Jeffrey Kluger, Science May Make it Impossible to Get Away With a Crime, Time Magazine, July 28, 2017.
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Discussion Six: How to Mark Your Genes
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1. Ray White & Jean-Marc Lalouel, Chromosome Mapping with DNA Markers, Scientific American, February 1988, 258(2), 40-48.
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2. Kevin A. Strauss, Genomics for the People, Scientific American, December 2015, 313(6), 66-73.
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3. Bonnie Rochman, Should Babies Be Sequenced? Scientific American, March 2017, 316: 72-75.
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Discussion Seven: Human Gene Therapy - The Beginning
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1. Inder M. Verma, Gene Therapy. Scientific American, November, 1990, 263(5), 68-84.
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2. Rick Lewis, Gene Therapy's Second Act, Scientific American, March 1, 2014, 310(3).
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Discussion Eight: Human Gene Therapy - Twenty-First Century Applications
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1. Leonard Petrucelli & Aaron D. Gitler, Unlocking The Mystery of ALS, Scientific American, June, 2017.
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2. Elie Dolgin, The Hexanucleotide Hex, Nature, October 19, 2017.
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3. Avery D. Posey, Jr., Carl H. June, & Bruce L. Levine Cancer Killers, Scientific American, March, 2017.
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Discussion Nine: The CRISPR Revolution
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1. Michael Specter, DNA Revolution, National Geographic Magzine, August 2016, 31-55.
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2. Annie Sneed, Mail-Order CRISPR Kits Allow Absolutely Anyone to Hack DNA, Scientific American, November 2, 2017.
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3. Michael Specter, The Gene Hackers, The New Yorker, November 16, 2015.
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Discussion Ten: Patenting Genes
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1. John S. Demott, Science: Test-Tube Life: Reg. U.S. Pat. Office, Time Magazine, June 30,1980.
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2. Gary Stix, Owning the stuff of Life, Scientific American, February, 2006, 294(2), 76-83.
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3. Adam Liptak, Justics, 9-0, Bar Patenting Human Genes, New York Times, June 13, 2013.
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4. Antonio Regalado, CRISPR Patent Fight Now a Winner-Take-All Match, MIT Technology Review, April 15, 2015.
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5. Andrew Pollack, Harvard and MIT Scientists Win Gene-Editing Patent Fight, New York Times, February. 15, 2017.
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