Selected Publications

Chen, M., Bui, A.Q., & Goldberg, R.B. (2020) Using giant scarlet runner bean (Phaseolus coccineus) embryos to dissect the early events in plant embryogenesis. in Plant embryogenesis: Methods and protocols , M. Bayer, Ed. (Springer Science+Business Media, 2020), 2122, 205-222. doi: 10.1007/978-1-0716-0342-0_15.
Jo, L., Pelletier, J.M., Hsu, S., Baden, R., Goldberg, R.B., Harada, J.J. (2019) Combinatorial interactions of the LEC1 transcription factor specify diverse developmental programs during soybean seed development. Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1918441117.
Chen, M., Lin, J., Hur, J., Pelletier, J.M., Baden, R., Pellegrini, M., Harada, J.J. and Goldberg, R.B. (2018) Seed genome hypomethylated regions are enriched in transcription factor genes. Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1811017115.
Henry, K.F., Bui, A.Q., Kawashima, T., Goldberg, R.B. (2018) A shared cis-regulatory module activates transcription in the suspensor of plant embryos. Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1805802115.
Lin, J.Y., Le, B.H., Chen, M., Henry, K.F., Hur, J., Hsieh, T.F., Pellegrini, M., Fischer, R.L., Harada, J.J., Goldberg, R.B. (2017) Similarity between soybean and Arabidopsis seed methylomes and loss of non-CG methylation does not affect seed development. Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1716758114.
Pelletier, J.M., Kwong, R. Park, S., Le, B.H., Baden, R., Cagliari, A., Hashimoto, M., Munoz, M., Fischer, R.L., Goldberg, R.B., Harada J.J. (2017) LEC1 sequentially regulates the transcription of genes involved in diverse developmental processes during seed development. Proc. Natl. Acad. Sci. USA, 114 :32, E6710–E6719. doi: 10.1073/pnas.1707957114.
Danzer, J., Mellott, E., Bui, A.Q., Le, B.H., Martin, P., Hashimoto, M., Perez-Lesher, J., Chen, M., Pelletier, J.M., Somers, D.A., Goldberg, R.B., Harada, J.J. (2015) Down-regulating the expression of 53 soybean transcription factor genes uncovers a role for SPEECHLESS in initiating stomatal cell lineages during embryo development, Plant Physiology, 168 :3, 1025-35. doi: 10.1104/pp.15.00432.
Henry, K.F. and Goldberg, R.B. (2015) Using scarlet runner bean embryos to uncover regulatory networks controlling suspensor gene activity. Frontiers in Plant Science, 6 :44.doi: 10.3389/fpls.2015.00044.
Henry, K.F., Kawashima, T., and Goldberg, R.B. (2015) A cis-regulatory module activating transcription in the suspensor contains five cis-regulatory elements. Plant Molecular Biology, 88 :3, 207-17. doi: 10.1007/s11103-015-0308-z.
Belmonte, M., Kirkbride, R.C., Stone, S.L., Pelletier, J.M., Bui, A.Q., Yeung, E.C., Hashimoto, M., Fei, J., Harada, C.M., Munoz, M.D., Le, B.H., Drews, G.N., Brady, S.M., Goldberg, R.B., and Harada, J.J. (2013) Comprehensive developmental profiles of gene activity in regions and subregions of the Arabidopsis seed. Proc. Natl. Acad. Sci. USA, 110 :5, E434-44. doi: 10.1073/pnas.1222061110.
Le, B.H., Cheng, C., Bui, A.Q., Wagmeister, J.A., Henry, K.F., Pelletier, J., Kwong, L., Belmonte, M., Kirkbride, R., Horvath, S., Drews, G.N., Fischer, R.L., Okamuro, J.K., Harada, J.J., and Goldberg, R.B. (2010) Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors. Proc. Natl. Acad. Sci USA, 170 :18, 8063-70. doi: 10.1073/pnas.1003530107.
Kawashima, T. and Goldberg, R.B. (2010) The suspensor: not just suspending the embryo. Trends In Plant Science, 15 :1, 23-30. doi: 10.1016/j.tplants.2009.11.002.
Kawashima, T., Wang, X., Henry, K.F., Bi, Y., Weterings, K., and Goldberg, R.B. (2009) Identification of cis - regulatory sequences that activate transcription in the suspensor of plant embryos. Proc. Natl. Acad. Sci. USA, 106 :9, 3627-32. doi: 10.1073/pnas.0813276106.
Goldberg, R.B. (2009) The Plant Cell: 20 Years Young. Plant Cell, 21 :1, 3-12. Editorial Article. doi: 10.1105/tpc.109.065888.
Stone S.L., Braybrook S.A., Paula S.L., Kwong L.W., Meuser J., Pelletier J., Hsieh T.F., Fischer R.L., Goldberg, R.B., and Harada J.J. (2008) Arabidopsis LEAFY COTYLEDON2 induces maturation traits and auxin activity: Implications for somatic embryogenesis. Proc. Natl. Acad. Sci. USA, 105 :8, 3151-56. doi: 10.1073/pnas.0712364105.
Ohr, H., Bui, A.Q., Le, H.B., Fischer, R.L., and Choi, Y. (2007) Identification of putative Arabidopsis DEMETER target genes by GeneChip Analysis. Biochem. Biophys. Res. Commun., 364 :4, 856-60. doi: 10.1016/j.bbrc.2007.10.092.
Le, B.H., Wagmaister, J.A., Kawashma, T., Bui, A.Q., Harada, J.J., and Goldberg, R.B. (2007) Using Genomics to Study Legume Seed Development. Plant Physiology, 144 :2, 562-74. doi: 10.1104/pp.107.100362.
Xiao, W., Brown, R.C., Lemmon, B.E., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (2006) Regulation of Seed Size by Hypomethylation of Maternal and Paternal Genomes. Plant Physiology, 142 :3, 1160-68. doi: 10.1104/pp.106.088849.
Xiao, W., Custard, K.D., Brown, R.C., Lemmon, B.E., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (2006) DNA Methylation Is Critical for Arabidopsis Embryogenesis and Seed Viability. Plant Cell, 18 :4, 805-14. Seed Institute Article. doi: 10.1105/tpc.105.038836.
Gehring, M., Huh, J.H., Hsieh, T.F., Penterman, J., Choi, Y., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (2006) DEMETER DNA Glycosylase Establishes MEDEA Polycomb Gene Self-Imprinting by Allele-Specific Demethylation. Cell, 124 :3, 495-506. Seed Institute Article. doi: 10.1016/j.cell.2006.12.034.
Braybrook, S.A., Stone, S.L., Park, S., Bui, A.Q., Le, B.H., Fischer, R.L., Goldberg,R. B., and Harada, J.J. (2006) Genes Directly Regulated by LEAFY COTYLEDON2 Provide Insight Into the Control of Embryo Maturation and Somatic Embryogenesis. Proc. Natl. Acad. Sci. USA, 103 :9, 3468-73. Seed Institute Article. doi: 10.1073/pnas.0511331103.
Yamagishi, K., Nagata, N., Yee, K.M., Braybrook, S.A., Pelletier, J., Fujioka, S., Yoshida, S., Fischer, R.L., Goldberg, R.B., and Harada, J.J. (2005) TANMEI/EMB2757 Encodes A WD Repeat Protein Required for Embryo Development in Arabidopsis. Plant Physiol., 139 :1, 163-73. Seed Institute Article. doi: 10.1104/pp.105.060467.
Sanders, P.M., Bui, A.Q., Le, B.H., and Goldberg, R.B. (2005) Differentiation and Degeneration of Cells That Play a Major Role in Tobacco Anther Dehiscence. Sex. Plant. Reprod, 17 :5, 219-41. doi: 10.1007/s00497-004-0231-y.
Ohto, M.A., Fischer, R.L., Goldberg, R.B., Nakamura, K., and Harada, J.J. (2005) Control of Seed Mass by APETALA2. Proc. Natl. Acad. Sci. USA, 102 :8, 3123-3128. doi: 10.1073/pnas.0409858102.
Goldberg, R.B. Field of Dreams: Science Makes Exciting Ag Advances, but "Natural" Naysayers Stand in Way. Commentary originally appeared in the Daily News of Los Angeles (CA) on December 5, 2004.
Choi, Y., Harada, J.J., Goldberg, R.B., Fischer, R.L. (2004) An Invariant Aspartic Acid in the DNA Glycosylase Domain of DEMETER is Necessary for Transcriptional Activation of the Imprinted MEDEA Gene. Proc. Natl. Acad. Sci. USA, 101 :19, 7481-86. Seed Institute Article. doi: 10.1073/pnas.0402328101.
Xiao, W., Gehring, M., Choi, Y., Margossian, L., Pu, H., Harada, J.J., Goldberg, R.B., Pennell, R.I., and Fischer, R.L. (2003) Imprinting of the MEA Polycomb Gene is Controlled by Antagonism Between MET1 Methyltransferase and DME Glycosylase. Dev Cell., 5 :6, 891-901. Seed Institute Article. doi: 10.1016/S1534-5807(03)00361-7.
Lee, H., Fischer, R.L., Goldberg, R.B., and Harada, J.J. (2003) Arabidopsis LEAFY COTYLEDON1 Represents a Functionally Specialized Subunit of the CCAAT Binding Transcription Factor. Proc. Natl. Acad. Sci. USA, 100 :4, 2152-56. Seed Institute Article. doi: 10.1073/pnas.0437909100.
Kwong, R.L., Bui, A.Q., Lee, H., Kwong, L.W., Fischer, R.L., Goldberg, R.B. , and Harada J.J. (2003) LEAFY COTYLEDON1-LIKE Defines a Class of Regulators Essential for Embryo Development. Plant Cell, 15 :1, 5-18. Seed Institute Article. doi: 10.1105/tpc.006973.
Choi, Y., Gehring, M., Johnson, L., Hannon, M., Harada, J.J., Goldberg, R.B., Jacobsen, S.E., and Fischer, R.L. (2002) DEMETER, a DNA Glycosylase Domain Protein Is Required for Endosperm Gene Imprinting and Seed Viability in Arabidopsis. Cell, 110 :1, 33-42. Seed Institute Article. doi: 10.1016/S0092-8674(02)00807-3.
Apuya, N.R., Yadegari, R., Fischer, R.L., Harada, J.J., and Goldberg, R.B. (2002) RASPBERRY3 Gene Encodes a Novel Protein Important for Embryo Development. Plant Physiology, 129 :2, 691-705. doi: 10.1104/pp.004010.
Weterings, K., Apuya, N. R., Bi, Y., Fischer, R.L., Harada, J.J., and Goldberg, R. B. (2001) Regional Localization of Suspensor mRNAs During Early Embryo Development. Plant Cell, 13 :11, 2409-25. Cover Article. Seed Institute Article. doi: 10.1105/tpc.010326.
Kinoshita, T., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (2001) Polycomb Repression of Flowering During Early Embryo Development. Proc. Natl. Acad. Sci. USA, 98 :24, 14156-61. Seed Institute Article. doi: 10.1073/pnas.241507798.
Stone, S.L., Kwong, L. W., Yee, K. M., Pelletier, J., Lepiniec, L., Fischer, R.L., Goldberg, R. B., and Harada, J.J. (2001) LEAFY COTYLEDON2 Encodes a B3 Domain Transcription Factor That Induces Embryo Development. Proc. Natl. Acad. Sci. USA, 98 :20, 11806-11. Seed Institute Article. doi: 10.1073/pnas.201413498.
Yadegari, R., Kinoshita, T., Lotan, O., Cohen, G., Katz, A., Choi, Y., Katz, A., Nakashima, K., Harada, J.J., Goldberg, R.B., Fischer, R.L., and Ohad, N. (2000) Mutations in the FIE and MEA Genes That Encode Interacting Polycomb Proteins Cause Parent-of-Origin Effects on Seed Development by Distinct Mechanisms. Plant Cell, 12 :12, 2367-81. Seed Institute Article. doi: 10.1105/tpc.12.12.2367.
Apuya, N.R., Yadegari, R., Fischer, R.L., Harada, J.J., Zimmerman, J.L., and Goldberg, R.B. (2001) The Arabidopsis Embryo Mutant Schlepperless Has a Defect in the Chaperonin-60α Gene . Plant Physiol., 126 :2, 717-30. Back Cover Article. Seed Institute Article. doi: 10.1104/pp.126.2.717.
Goldberg, R.B. (2001) From Cot Curves to Genomics: How Gene Cloning Established New Concepts in Plant Biology. Plant Physiol., 125 :1, 4-8. doi: 10.1104/pp.125.1.4.
Sanders, P.M., Lee, P.Y., Biesgen, C., Boone, J. D., Beals, T.P., Weiler, E.W., and Goldberg, R.B. (2000) The Arabidopsis DELAYED DEHISCENCE1 Gene Encodes an Enzyme in the Jasmonic Acid Synthesis Pathway. Plant Cell, 12 :7, 1041-61. Cover Article. doi: 10.1105/tpc.12.7.1041.
Sanders, P.M., Bui, A.Q., Weterings, K., McIntire, K.N., Hsu, Y-C., Lee, P.Y., Truong, M. T., Beals, T.P., and Goldberg, R.B. (1999) Anther Developmental Defects in Arabidopsis Thaliana Male-Sterile Mutants. Sex. Plant. Reprod., 11 :6, 297-322. doi: 10.1007/s004970050.
Ohad, N., Yadegari, R., Margossian, L., Hannon, M., Michaeli, D., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (1999) Mutations in FIE , a WD Polycomb Gene, Allow Endosperm Development Without Fertilization. Plant Cell, 11 :3, 407-15. doi: 10.1105/tpc.11.3.407.
Kiyosue, T., Ohad, N., Yadegari, R., Hannon, M., Dinney, J., Wells, D., Katz, A., Margossian, L., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (1999) Control of Fertilization-Independent Endosperm Development by the MEDEA Polycomb Gene in Arabidopsis. Proc. Natl. Acad. Sci. USA, 96 :7, 4186-91. doi: 10.1073/pnas.96.7.4186.
Kinoshita, T., Yadegari, R., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (1999) Imprinting of the MEDEA Polycomb Gene in the Arabidopsis Endosperm. Plant Cell, 11 :10, 1945-52. Seed Institute Article. doi: 10.1371/journal.pgen.1000663.
Van Rhijn, P., Goldberg, R.B., and Hirsch, A.M. (1998) Lotus Corniculatus Nodulation Specificity Is Changed By the Presence of a Soybean Lectin Gene. Plant Cell, 10 :8, 1233-49. Cover Article. doi: 10.1105/tpc.10.8.1233.
Lotan, T., Ohto, M., Yee, K.M., West, M.A.L., Lo, R., Kwong, R.W., Yamagishi, K., Fischer, R.L., Goldberg, R. B., and Harada, J. J. (1998) Arabidopsis LEAFY COTYLEDON1 is Sufficient to Induce Embryo Development in Vegetative Cells. Cell, 93 :7, 1195-1205. Seed Institute Article. doi:10.1016/S0092-8674(00)81463-4.
Dunn, S.M., Drews, G.N., Fischer, R.L., Harada, J.J., Goldberg, R.B., and Koltunow, A.M. (1997) First: An Arabidopsis Mutant With Altered Cell Division Planes and Radial Pattern Disruption During Embryogenesis. Sex. Plant. Reprod., 10 :6, 358-67. Seed Institute Article. doi: 10.1007/s004970050.
Yadegari, R. and Goldberg, R.B. (1997) Embryogenesis in Dicotyledonous Plants. In: Cellular and Molecular Biology of Plant Seed Development, B. A. Larkins and I. K. Vasil, eds., Kluwer Press, pp. 3-52. doi: 10.1007/978-94-015-8909-3_1.
Beals, T.P. and Goldberg, R.B. (1997) A Novel Cell Ablation Strategy Blocks Tobacco Anther Dehiscence. Plant Cell, 9 :9, 1527-45. Cover Article . doi: 10.1105/tpc.9.91527.
Goldberg, R.B., Sanders, P.M., and Beals, T.P. (1995) A Novel Cell-Ablation Strategy for Studying Plant Development. Phil. Trans. R. Soc., 350 :1331, 5-17. doi: 10.1098/rstlb.1995.0131.
Yadegari, R., de Paiva, G. ., Laux, T., Koltunow, A.M., Apuya, N., Zimmerman, J.L., Fischer, R.L., Harada, J.J., and Goldberg, R B. (1994) Cell Differentiation and Morphogenesis are Uncoupled in Arabidopsis Raspberry Embryos. Plant Cell, 6 :12, 1713-29. Cover Article. doi: 10.1105/tpc.6.12.1713.
West, M.A.L., Yee, K. M., Dano, J., Zimmerman, J.L., Fischer, R.L., Goldberg, R.B., and Harada, J.J. (1994) LEAFY COTYLEDON 1 is an Essential Regulator of Late Embryogenesis and Cotyledon Identity in Arabidopsis. Plant Cell, 6 :12, 1731-45. Seed Institute Article. doi: 10.1105/tpc.6.12.1731.
Goldberg, R.B., de Paiva, G., and Yadegari, R. (1994) Plant Embryogenesis: Zygote to Seed. Science, 266 :5185, 605-14. doi: 10.1126/science.266.5185.605.
Goldberg, R.B., Beals, T.P., and Sanders, P.M. (1993) Anther Development: Basic Principles and Practical Applications. Plant Cell, 5 :10, 1217-29. doi: 10.1105/tpc.5.10.1217.
Perez-Grau, L. and Goldberg, R.B. (1989) Soybean Seed Protein Genes are Regulated Spatially During Embryogenesis. Plant Cell, 1 :11, 1095-1109. doi: 10.1105/tpc.1.11.1095.
Jofuku, K.D. and Goldberg, R.B. (1989) Kunitz Trypsin Inhibitor Genes are Differentially Expressed During the Soybean Life Cycle and in Transformed Tobacco Plants. Plant Cell, 1 :11, 1079-93. doi: 10.1105/tpc.1.11.1079.
Jofuku, K.D., Schipper, R.D,. and Goldberg, R.B. (1989) A Frameshift Mutation Prevents Kunitz Trypsin Inhibitor mRNA Accumulation in Soybean Embryos. Plant Cell, 1 :4, 427-35. doi: 10.1105./tpc.1.4.427. Erratum in: Plant Cell , 1 :5, 567.
Goldberg, R.B. (1988) Plants: Novel Developmental Processes. Science, 240 :4858, 1460-67.
Barker, S.J., Harada, J.J., and Goldberg, R.B. (1988) Cellular Localization of Soybean Storage Protein mRNA in Transformed Tobacco Seeds. Proc. Natl. Acad. Sci. USA, 85 :2, 458-62.
Walling, L., Drews, G.N., and Goldberg, R.B. (1986) Transcriptional and Posttranscriptional Regulation of Soybean Seed Protein Messenger-RNA Levels. Proc. Natl. Acad. Sci. USA, 83 :7, 2123-27.
Okamuro, J.K., Jofuku, K.D., and Goldberg, R.B. (1986) Soybean Seed Lectin Gene and Flanking Nonseed Protein Genes are Developmentally Regulated in Transformed Tobacco Plants. Proc. Natl. Acad. Sci. USA, 83 :21, 8240-44.
Kamalay, J.C. and Goldberg, R.B. (1984) Organ-Specific Nuclear RNAs in Tobacco. Proc. Natl. Acad. Sci. USA, 81 :9, 2801-5.
Kamalay, J.C. and Goldberg, R.B. (1980) Regulation of Structural Gene Expression in Tobacco. Cell, 19 :4, 935-46. doi: 10.1016/0092-8674(80)90085-9.
Goldberg, R.B., Hoschek, G., Kamalay, J.C., and Timberlake, W.E. (1978) Sequence Complexity of Nuclear and Polysomal RNA In Leaves of the Tobacco Plant. Cell, 14 :1,123-31. doi: 10.1016/0092-8674(78)90307-0.