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Course Info: |
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Units: |
5.0 |
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Lectures: |
Tuesday & Thursday : 3:30 - 6:00 PM |
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Location: |
La Kretz 120 |
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Discussions: |
Wednesday: 1:00 - 3:00 PM William Barshop (La Kretz 100)
Wednesday: 3:00 - 5:00 PM Dominic Saadi (La Kretz 100)
Wednesday: 5:00 - 7:00 PM Dominic Lucido (La Kretz 100)
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Office Hours: |
Monday: 3:00PM - 5:00PM Dominic Lucido (Hershey Hall 318)
Tuesday: 1:00PM - 3:00PM Dominic Saadi (Hershey Hall 318)
Friday: 2:00PM - 4:00PM William Barshop (Hershey Hall 318)
Monday: 12:00PM - 1:00PM Dr. Bob Goldberg (Terasaki Life Sci 4121)
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Class Video |
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Class Syllabus |
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Class Handouts and Powerpoint Presentation
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Week 1
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03/31/15 - Lecture One Handout (pdf): The Age of DNA: What is Genetic Engineering? (Part One)
04/02/15 - Film: Gene Egineers: Playing God
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Week 2
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04/07/15 - Lecture Two Handout (pdf): The Age of DNA: What is Genetic Engineering? (Part Two)
04/09/15 - Film: Race for the Double Helix
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Week 3
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04/14/15 - Lecture Three Handout (pdf): What Are Genes & How Do They Work: (Part One)
04/16/15 - Guest Speaker Handout (pdf):
Engineering Crops For the Developing World by Dr. Prakash
GMO and Public Policy by Dr. McHughen
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Week 4
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04/21/15 - Lecture Four Handout (pdf): What Are Genes & How Do They Work: (Part Two)
04/23/15 - Film: Conviction
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Week 5
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04/28/15 - Lecture Five Handout (pdf): The Nuts $amp; Bolts of Genetic Engineering: The Factor VIII Story From Gene To Drug
04/30/15 - Guest Speaker Handout (pdf): An Introduction to DNA Forensics Analysis & Crime Scene Investigation by Harry Klann from LAPD DNA Unit
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Week 6
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05/05/15 - All-Class Midterm Oral Exam
05/07/15 - Lecture Six Handout (pdf): Twenty-First Century Genetic Engineering Applications
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Week 7
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05/12/15 - Lecture Seven Handout (pdf): Age of Genomics-Identifying Individuals Past & Present Using DNA
05/14/15 - Guest Speaker Handout (pdf): In Vitro Fertilization & Genetic Testing by Dr. Michele Evans
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Week 8
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05/19/14 - Lecture Eight Handout (pdf) by Dr. John Harada: Human Genetic Engineering & Gene Therapy
05/21/15 - Guest Speaker Handout (pdf): Stem Cell Biology and Ethics by Dr. Pei Yun Lee
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Week 9
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05/26/15 - Lecture Nine Handout (pdf): Science & the Constitution: Regulating Science & GMO
05/28/15 - Lecture Ten Handout (pdf): Science & the Constitution: Who Owns Your Genes?
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Week 10
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06/02/15 - Final All-Class Oral Exam
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Guest Speakers (Click on the name for information about the speaker) |
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Dr. Channapatna Prakash, Ph.D.
Professor in Plant Molecular Genetics, Tuskegee University
Title: Engineering Crops for the Developing World
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Dr. Alan McHughen, Ph.D.
CE Plant Biotechnologist, Department of Plant Sciences, UC Riverside
Title: GMO and Public Policy
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Dr. PeiYun Lee, Ph.D.
UCLA Department of Molecular, Cell, and Developmental Biology
Title: Stem Cells Biology and Ethics |
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Dr. Michele Evans, M.D., FACOG
Reproductive Specialist, Pacific Fertility Center Los Angeles
Title: In Vitro Fertilization & Genetic Testing |
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Harry Klann
Supervising Criminologist, DNA Unit, LAPD
Title: DNA Forensics & The Law |
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Articles For Discussion |
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1. Stanley N. Cohen, The Manipulation of Genes, Scientific American, June, 1992, 233(1), 24-33.
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2. Stanley N. Cohen, DNA Cloning: A personal view after 40 years, PNAS, September 23, 2013, 110(39), 15521-15529.
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3. Clifford Grobstein, The Recombinant DNA Debate, Scientific American, July, 1977, 237(1), 22-33.
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1. Walter Gilbert and Lydia Villa-Komaroff, Useful Proteins From Recombinant Bacteria, Scientific American, April, 1980, 242(4), 74-94.
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1. Charles S. Gasser and Robert T. Fraley, Transgenic Crops, Scientific American, June, 1992, 266(6), 62-69.
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2. David H. Freedman, Are Engineered Foods Evil?, Scientific American, September, 2013, 80-85.
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3. Mark Lynas, Lecture to Oxford Farming Conference, www.marklynas.org/2013/01/lecture-to-oxford-farming-conference-3-january-2013/.
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1. Ray White & Jean-Marc Lalouel, Chromosome Mapping with DNA Markers, Scientific American, February 1988, 258(2), 40-48.
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2. Mark A. Rothstein, Keeping Your Genes Private, Scientific American, September 2008, 299(3), 64-69.
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3. Melissa Healy, DNA Sequencer raises doctors' hopes for personalized medicine, LA Times, January 3, 2014.
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4. Bonnie Rochman, The DNA Dilemma: A Test That Could Change Your Life, Time Magzine, December 24, 2012.
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5. Andrew Pollack, DNA Blueprint for Fetus Built Using Tests of Parents, New York Time, June 6, 2012.
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1. Peter J. Neufeld & Neville Coleman, When Science Takes the Witness Stand, Scientific American, May, 1990, 262(5), 46-53.
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2. Caitlin Smith, Stephen Strauss, & Laura DeFrancesco, DNA Goes to Court, Nature Biotechnology, November, 2012, 30(11), 1047-1052.
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3. Clyde Haberman, DNA Analysis Exposes Flaws in an Inexact Forensic Science, The New York Times, May 18, 2014.
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1. William H. Velander, Henryk Lubon, & William N. Drohan, Transgenic Livestock as Drug Factories, Scientific American, January 1997, 276(1), 70-74.
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2. Gary Stix, The Land of Milk & Honey, Scientific American, November 2005, 293(5), 102-104.
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3. New Antithrombin Drug, ATryn, Approved by FDA, National Blot Clot Alliance Website.
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4. Ian Wilmot, Cloning For Medicine, Scientific American, December 1998, 279(6), 58-63.
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5. GM Salmon: FDA's Assessment of Risks, Los Angeles Times, December 24, 2012.
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6. Amy Maxmen, Politics Holds Back Animal Engineers, Nature, October 18, 2012, 490, 318-319.
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1. Clive Cookson et al., The Future of Stem Cells. Scientific American Special Report, July, 2005, A6-A21.
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2. Konrad Hochedlinger, Your Inner Healers. Scientific American, May, 2010, 302(4), 47-53.
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3. Stephen S. Hall, Diseases in a Dish. Scientific American, March, 2011, 304(3), 41-45.
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4. Robin Marantz Henig, Pandora's Baby. Scientific American, June, 2003, 266(6), 63-68.
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1. Inder M. Verma, Gene Therapy. Scientific American, November, 1990, 263(5), 68-84.
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2. Rick Lewis, Gene Therapy's Second Act Scientific American, March 1, 2014, 310(3).
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3. Margaret Knox, Is the Gene-Editing Revolution Finally Here? Scientific American, November 18, 2014, 311(6).
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4. David Cyranoski DNA Editing of Human Embryos Alarms Scientists, Scientific American, March 13, 2015.
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1. Science: Test-Tube Life: Reg. U.S. Pat. Office, Time Magazine, June 30,1980.
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2. Gary Stix, Owning the stuff of Life, Scientific American, February, 2006, 294(2), 76-83.
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3. Adam Liptak, Justics, 9-0, Bar Patenting Human Genes, New York Times, June 13, 2013.
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4. Albert Wai-Kit Chan et. al.,A Patent Perspective on US Stem Cell Research, Nature Biotechnology, July 8, 2014, 32, 633-637
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5. Andrew Pollack, Myriad Genetics Ending Patent Dispute on Breast Cancer Risk Testing, The New York Times, Janurary 27, 2015.
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